Endocrine Abstracts

Introduction: Diabetes is a chronic condition which has become a major public health concern approaching epidemic proportions globally. Effective diabetes management often presents many challenges. Clinicians and patients often become overwhelmed by the need to address co-morbid chronic conditions in addition to patients’ diabetes-specific treatment goals. It is widely accepted that bariatric surgery can help improve health in a range of metabolic diseases, including T2D...

Background: Pegylated interferon-alpha (IFN-α) is licensed as an antiviral, immunomodulatory and anti-proliferative therapy, but may induce autoimmune conditions including Type 1 diabetes Mellitus/latent Autoimmune Diabetes of Adults (LADA). Case Report: A 50-year-old male presented with a 3-week history of polyuria, polydipsia and weight loss. Following review by his General Practitioner he was found to have an elevated serum glucose (55.4 mmol/l)....

Introduction: Granulomatosis with polyangiitis (GPA) is an anti-neutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitis of both small and medium-sized vessels. Pituitary involvement in GPA is uncommon and few cases have been previously reported. Isolated pituitary involvement in GPA is rare and 96% of cases are associated with other organ involvement. GPA commonly affects the upper respiratory tract (93%), lungs (73%) and kidneys (67%).Case...

Introduction: Resolution of pituitary tumour without surgical intervention is rare. The mechanism of spontaneous resolution of pituitary adenoma is unclear but may be explained by either pituitary apoplexy or hypophysitis responding to steroids. Bray BP, et al(2021) reported the case of vanishing pituitary mass due pituitary apoplexy. Park SM, et al (2014) reported 22 cases of pituitary mass due hypophysititis which improved mostly with medical therapy.C...